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Breast cancer develops when the breast cells and tissues grow out of control and become cancerous. A lump in the breast, a change in how your breast appears or feels, fluid discharge from the nipple, an inverted nipple, dimpling of the skin, or a scaly or red patch of skin are all indications of breast cancer.

When breast cancer is at an advanced stage with an extensive spread of the disease, the patient may experience bone pain, yellow skin, swollen lymph nodes, or dyspnea (shortness of breath).

Tumor size is one of the most critical factors in determining the stage of breast cancer, says Dr. Garvit Chitkara, an acclaimed breast cancer surgeon in Mumbai.

There are a total of 4 primary stages of breast cancer.The stage offers a uniform approach to describing the malignancy for clinicians to collaborate and develop the most effective treatment plans.

Breast cancer and the TNM staging system

Breast cancer and the TNM staging system

The TNM staging system for breast cancer describes the extent of cancer in the body. It is made up of 3 parts:

T –Tumor stage

N – Nodestage

M – Metastasisstage

T – Tumor stage

There are 5 classifications for breast cancer tumors based on size:

T0: A tumor this size is regarded as non-invasive. It has not spread and is very little.

T1: This cancerous growth measures less than 2 cm and may or may not have extended to the lymph nodes nearby.

T2: This tumor is slightly bigger and ranges from 2 to 5 cm. Some tumors may be bigger but have not yet started to spread (metastasized) to the lymph nodes nearby. Others stage 2 tumors may have spread to nearby lymph nodes despite being small.

T3: The tumor measures more than 5 cm.

T4: This tumor may be of any size but has invaded the skin or chest wall.

N – Node stage

Determining whether neighboring lymph nodes have been affected also contributes to breast cancer staging. In order to achieve this, a clinical examination, ultrasound, FNAC or one or more lymph nodes from the armpit are removed and examined under a microscope.

The lymph node status is classified as:

N-0: Swollen nodes cannot be felt.

N-1:Some swelling may be felt in some nodes that could be cancerous.

N-2: The lymph nodes have clumped together and are swollen and lumpy.

N-3: There are swollen lymph nodes above the collarbone.

M – Metastasis stage

The eminent breast oncology surgeon in Mumbai, Dr. Garvit Chitkara, says that The occurrence of metastasis shows that cancer has spread to an area of the body other than the original site.

M-0: There is no spread of cancer other than in the breasts and nearby lymph nodes

M-1: . The cancer cells have spread to other parts of the body and have formed malignant deposits there.

What are the factors that affect breast cancer stages and its treatment?

Status of hormone receptor

Status of hormone receptor

Receptors are proteins that react to the hormones progesterone and estrogen.Medical professionals classify breast cancer asestrogen receptors (ER-positive or estrogen receptor-positive) and progesterone receptors (PgR-positive or progesterone receptors-positive).

The most successful treatment for cases involving hormone receptors is typically hormone therapy.

Status of HER2 gene (human epidermal growth factor receptor 2)

Healthy breast cells’ development, division, and repair are all regulated by the HER2 receptor protein. Doctors check the HER2 receptor level to see if it is higher than expected. Higher HER2 receptor level causes the cells to grow and mutate abnormally fast and the tumor is classified as HER2 positive

In these circumstances, targeted medicines typically perform well.

Status of HER2 gene (human epidermal growth factor receptor 2)

Grade of the cancer cells

Grade of the cancer cells

Doctors classify cancer cells compared to non-cancerous cells based on their appearance under the microscope. Low-grade cancer cells are those that closely resemble healthy ones. The growth of these cancer cells is slower. High-grade cancer cells are recognized as being distinct from normal cells and have the propensity to multiply quickly.

A doctor might employ systemic treatments for these, such as hormone therapy, chemotherapy, targeted therapy, and other treatments. Radiation could also be utilized for cancer in its advanced stages, but it is more likely to be combined with other treatments.

Dr. Garvit Chitkara, a highly experienced breast surgical oncologist in Mumbai, adds that the tumor’s size and location (spread) are critical components in determining the stage of breast cancer and suitable treatment.

Despite this, doctors also take into account several additional factors, such as:

  • Age
  • General wellbeing
  • Individual preferences when recommending potential treatments

Conclusion

Breast tissue can develop breast cancer for years without any obvious lumps or bumps. Regular mammography might help detect the tumor earlier than you can through self-examinations.

The size of the tumor plays a significant role in the staging of breast cancer and can influence a patient’s prognosis and available treatments. When the tumors are minor, early detection by medical professionals can make managing and treating them easier.

Conclusion

The likelihood of a successful outcome increases with how early in stage breast cancer tumor is discovered. Early-stage malignancies often respond well to treatment. Your chance of developing metastases and life-threatening diseases can be significantly reduced if the cancer is detected early.

If you or a loved one suspects breast cancer, please visit Dr. Garvit Chitkara, a top-notch breast cancer surgeon in Mumbai, as soon as possible. He has over 15 years of expertise and is one of the preferred surgeons for people seeking breast cancer surgery in Mumbai.

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